Pediatric specialists, evaluate children with genetically defined, primary immune defects that lead to recurrent serious infection in childhood and adolescents. For these patients, bone marrow transplant or gene therapy, where appropriate, are used for immune reconstitution.

Children and adolescents with HIV infection and other diseases that lead to secondary, not genetically defined immune defects, are evaluated and treated. Physicians, Nurse Specialists, Pediatric Nurse Practitioners, Social Workers and Laboratory Technologists formulate treatment protocols for these children.

Adults with frequent pneumonias, sinus infections and other unusual infections are evaulated and treated.